Evidence · condition
Alcohol use disorder
LAST REVIEWED 2026-09-22 · PILOT / OBSERVATIONAL · NOT PROVEN
AUD human evidence for ibogaine remains early. Pilot open-label and observational program reports exist; they are not FDA approval and not a reason to self-treat.
Evidence: Very limitedNot provenNo dosing
Is ibogaine proven for alcohol use disorder?
No — not established. An IND or early-phase noribogaine research action is not AUD approval.
- Evidence level
- Very limited human evidence
- What is not proven
- Ibogaine or noribogaine as FDA-approved AUD treatment
- Safety
- Safety / QTc
- Self-treatment
- DIY refusal
What exists (source-labeled)
Rocha JM et al., Trends Psychiatry Psychother 2026. PMID 42520175, DOI 10.47626/2237-6089-2026-1437. Pilot open-label — not confirmatory. No dosing reproduced.
Armstrong SB et al., Mil Psychol 2024. PMID 38377244. Ibogaine and 5-MeO-DMT program observations — not an AUD RCT.
Regulatory adjacency: FDA-approval claim check.
Skipped: Research Square preprint PMID 41960323 (not promoted as peer-reviewed primary).