Evidence · condition
Traumatic brain injury
LAST REVIEWED 2026-09-22 · OBSERVATIONAL · NOT PROVEN
Veteran magnesium–ibogaine observational work (clinical + imaging) drew attention. Design limits stay on the page; ibogaine is not established TBI standard care.
Is ibogaine proven for TBI?
No — not established as TBI standard care.
- Evidence level
- Limited observational
- What is not proven
- FDA-approved or guideline TBI treatment
- Safety
- Safety / QTc
What exists (source-labeled)
Cherian KN et al., Nat Med 2024. PMID 38182784, DOI 10.1038/s41591-023-02705-w. Open-label observational — not confirmatory. No dosing reproduced.
Sridhar M et al., Biol Psychiatry Cogn Neurosci Neuroimaging 2026. PMID 41687815, DOI 10.1016/j.bpsc.2026.02.001. Imaging correlates — not confirmatory clinical efficacy.
Geoly AD et al., iScience 2026. PMID 41883580, DOI 10.1016/j.isci.2026.115121. Structural MRI endpoints — not a stand-alone efficacy RCT.
Gorman DM, Int J Drug Policy 2026. PMID 42330793. Critique — critique card.
Skipped
12-month MISTIC durability preprint was not promoted as peer-reviewed primary.
Media / continue
Dickinson extract · Capones · PTSD · OUD