Clinical boundary Schedule I in the U.S. Serious cardiac risk Not FDA-approved No dosing or referrals Schedule I · cardiac risk Not FDA-approved · no referrals

Sources

Source catalog

A public catalog of papers, trials, laws, policy records, podcasts, documentaries, books, cultural sources, claim records, and reference pages.

Sources indexed346

Browse the catalog

Search every indexed source or filter by type. Each result links to the original — the catalog is a finding aid, so open the source before relying on a claim.

Podcasts and interviews 66
News, articles, and blogs 62
Laws and policy 52
State policy coverage 51
Studies and papers 37
Clinics 18
Clinical trials 15
Books and bibliographies 10
Companies and patents 9
Culture and stewardship 9
Evidence pages 8
Weekly brief 5

Source types

Journalism155

Podcast Interview64

State Policy Coverage Row51

Policy Tracker Row17

Peer Reviewed Study14

Clinical Trial Registry9

Condition Evidence Template8

State Policy3

Clinic Observatory Schema2

Company Release2

Confidence labels

Primary-source record181

Media metadata64

State policy coverage row51

Peer-reviewed paper11

Registry record9

Evidence framework7

Peer-reviewed source6

Case report3

Claim record3

Cultural Stewardship2

Wanted sources

These are the gaps that would most improve the public reference.

Catalog preview

Source type: StudyConfidence: High

Magnesium-ibogaine therapy in veterans with traumatic brain injuries

Prospective open-label observational study of 30 male special-operations veterans who independently received magnesium-ibogaine treatment at Ambio Life Sciences in Mexico, with Stanford assessments before and after. The paper reports large short-term improvements and no unexpected serious adverse events, while stating that controlled clinical trials are needed.

Studies and papers · Nature Medicine

Source
Source type: StudyConfidence: High

Magnesium-ibogaine therapy effects on cortical oscillations and neural complexity in veterans with traumatic brain injury

Follow-up Nature Mental Health article on EEG and neural-complexity measures in the same broad magnesium-ibogaine veteran TBI research lane. It reports neurophysiological changes after treatment and states that controlled trials are needed to confirm findings.

Studies and papers · Nature Mental Health

Source
Source type: StudyConfidence: Low

Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis

Two-patient case report involving Ambio-affiliated authors and Ambio treatment records. Treat as preliminary case-report evidence with prominent conflict-of-interest and funder-involvement labels, not proof of efficacy.

Studies and papers · Frontiers in Immunology

Source
Source type: StudyConfidence: Low

Ibogaine for the treatment of Parkinson's disease: a case report

Track as exciting but very preliminary. One patient, low-dose course, validated PD instruments, no adverse events recorded, sleep worsened; not efficacy proof.

Studies and papers · source_radar

Source
Source type: StudyConfidence: High

Accelerated recovery using magnesium ibogaine: subjective experience analysis

Qualitative analysis from the 30-person MISTIC veteran cohort; interpret alongside open-label design limits.

Studies and papers · source_radar

Source
Source type: StudyConfidence: High

Mystical experiences during magnesium-Ibogaine associated with PTSD symptom improvements in veterans

Track as 30-male-veteran secondary analysis from MISTIC; association does not prove mechanism or general efficacy.

Studies and papers · source_radar

Source
Source type: StudyConfidence: High

Magnesium-ibogaine therapy effects on cortical oscillations and neural complexity

Track as follow-on analysis from the veteran TBI research line.

Studies and papers · source_radar

Source
Source type: StudyConfidence: High

Efficient and modular synthesis of ibogaine and related alkaloids

Important for supply, analog research, and non-plant-derived chemistry coverage.

Studies and papers · source_radar

Source
Source type: StudyConfidence: Moderate

A study of oral ibogaine in opioid withdrawal

Track recruitment/status, sponsor, eligibility criteria, and posted results.

Studies and papers · source_radar

Source
Source type: StudyConfidence: High

Veterans Say an Illegal Psychedelic Drug Is Helping Them. Now Mississippi Wants to Study Ibogaine. - Mississippi Free Press

Research source from Mississippi Free Press. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Mississippi Free Press

Source
Source type: CultureConfidence: High

Ibogaine’s Surge in Popularity Could Be a Huge Loss for the Gabonese People Unless We Shift Course - psychedelicalpha.com

Culture or stewardship source from psychedelicalpha.com. Outsider summaries require humility and source awareness.

Culture and stewardship · psychedelicalpha.com

Source
Source type: StudyConfidence: Moderate

Ibogaine and 5-MeO-DMT for addiction treatment with Garyth Moxey

Research source from Psychedelic Therapy Frontiers. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Psychedelic Therapy Frontiers

Source
Source type: StudyConfidence: High

Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis - Frontiers

Research source from Frontiers. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Frontiers

Source
Source type: StudyConfidence: High

Induction of insulin secretion by an aqueous extract of Tabernanhte iboga Baill. (Apocynaceae) in rat pancreatic islets of Langerhans - ScienceDirect

Research source from ScienceDirect. Study design, sample size, limitations, and safety signals matter.

Studies and papers · ScienceDirect

Source
Source type: StudyConfidence: High

Study Identifies Compounds Similar to Ibogaine That May Improve Treatment of Opioid Addiction - Association of American Universities (AAU)

Research source from Association of American Universities (AAU). Study design, sample size, limitations, and safety signals matter.

Studies and papers · Association of American Universities (AAU)

Source
Source type: StudyConfidence: High

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias - Wiley Online Library

Research source from Wiley Online Library. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Wiley Online Library

Source
Source type: LawConfidence: High

A Texas hallucinogen hub? $100 million for ibogaine testing brings leading firm to Austin - MSN

Law or policy source from MSN. Read the exact source before drawing legal conclusions.

Laws and policy · MSN

Source
Source type: StudyConfidence: High

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes - Frontiers

Research source from Frontiers. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Frontiers

Source
Source type: LawConfidence: High

Bush: Ibogaine saved my family - A Mississippi veteran’s perspective - RedHillsMSNews.com

Law or policy source from RedHillsMSNews.com. Read the exact source before drawing legal conclusions.

Laws and policy · RedHillsMSNews.com

Source
Source type: StudyConfidence: High

Response to Luz & Mash on cardiac toxicity of ibogaine - Schellekens - 2022 - Addiction - Wiley Online Library

Research source from Wiley Online Library. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Wiley Online Library

Source
Source type: StudyConfidence: High

Ohio lawmakers consider joining other states to test psychedelic-assisted treatments - Ohio Capital Journal

Research source from Ohio Capital Journal. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Ohio Capital Journal

Source
Source type: StudyConfidence: High

Texas to launch independent psychedelic study after drug companies miss mark - FOX 7 Austin

Research source from FOX 7 Austin. Study design, sample size, limitations, and safety signals matter.

Studies and papers · FOX 7 Austin

Source
Source type: StudyConfidence: High

Legislative updates in Mississippi, West Virginia, Oregon, and New Hampshire; Fast-tracked federal approval of Compass's synthetic psilocybin was vetoed; Federal bill proposes VA study psychedelics - The Microdose | Substack

Research source from The Microdose | Substack. Study design, sample size, limitations, and safety signals matter.

Studies and papers · The Microdose | Substack

Source
Source type: StudyConfidence: High

Protective effect of the aqueous extract of Tabernaemontana stapfiana (Apocynaceae) stem bark against monosodium glutamate-induced neurotoxicity in Swiss albino mice.

Research source from IBRO neuroscience reports. Study design, sample size, limitations, and safety signals matter.

Studies and papers · IBRO neuroscience reports

Source
Source type: StudyConfidence: High

Rare but relevant: Ibogaine and cardiovascular complications-prolonged QT interval and ventricular arrhythmias.

Research source from Addiction (Abingdon, England). Study design, sample size, limitations, and safety signals matter.

Studies and papers · Addiction (Abingdon, England)

Source
Source type: StudyConfidence: High

Exploring the Use of Ibogaine in Opioid Recovery: Insights from Lived Experience.

Research source from Journal of psychoactive drugs. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Journal of psychoactive drugs

Source
Source type: StudyConfidence: Moderate

Ibogaine in the Treatment of Alcoholism: an Open-label Escalating-dose Trial

COMPLETED

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: High

From monotherapy to sequential models: An updated scoping review on ibogaine's role in treatment for psychiatric disorders.

Research source from Journal of psychopharmacology (Oxford, England). Study design, sample size, limitations, and safety signals matter.

Studies and papers · Journal of psychopharmacology (Oxford, England)

Source
Source type: StudyConfidence: High

Development of Bioisosteres of Iboga Alkaloids: A Step-Economical Synthesis to Enhance the Antinociceptive and Anxiolytic Activity with Neuroprotective Effects.

Research source from ACS pharmacology & translational science. Study design, sample size, limitations, and safety signals matter.

Studies and papers · ACS pharmacology & translational science

Source
Source type: StudyConfidence: High

Blinding Integrity in Psychedelic Randomized Clinical Trials: A Systematic Review.

Research source from JAMA psychiatry. Study design, sample size, limitations, and safety signals matter.

Studies and papers · JAMA psychiatry

Source
Source type: StudyConfidence: High

Oral 18-methoxycoronaridine activity in simian and murine Leishmania amazonensis infection.

Research source from Frontiers in pharmacology. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Frontiers in pharmacology

Source
Source type: StudyConfidence: High

Unlocking the cytotoxic potential of Apocynaceae monoterpene indole and bis-indole alkaloids: a review.

Research source from Natural product research. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Natural product research

Source
Source type: StudyConfidence: High

Tabernaemontana catharinensis: A Source of Indole Alkaloids With Potential Activity as Chemotherapeutic Agents.

Research source from Chemistry & biodiversity. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Chemistry & biodiversity

Source
Source type: StudyConfidence: High

US speeds up research into mind-altering drugs - including mysterious 'ibogaine'.

Research source from Nature. Study design, sample size, limitations, and safety signals matter.

Studies and papers · Nature

Source
Source type: MediaConfidence: High

Psychedelic Stocks Rally After Trump’s Executive Order - Forbes

News or commentary from Forbes. Use it to understand public discussion and timing; verify important claims against primary sources.

News, articles, and blogs · Forbes

Source
Source type: StudyConfidence: Moderate

Personality and Drug Use (PDU)

WITHDRAWN

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: Moderate

Trifecta Research Study

WITHDRAWN

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: Moderate

Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification

COMPLETED

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: Moderate

Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure

ACTIVE_NOT_RECRUITING

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: Moderate

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

RECRUITING

Studies and papers · ClinicalTrials.gov

Source
Source type: StudyConfidence: Moderate

Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers

COMPLETED

Studies and papers · ClinicalTrials.gov

Source
Source type: TrialConfidence: High

FDA allows early-phase noribogaine hydrochloride study for alcohol use disorder to proceed

Important policy and research signal. FDA permission to proceed is not approval, safety proof, or efficacy proof.

Clinical trials · source_radar

Source
Source type: TrialConfidence: Moderate

UTMB Health and UTHealth Houston awarded $50M to lead ibogaine clinical trials

Track consortium members, trial registration, matching funds, and protocol publication.

Clinical trials · source_radar

Source
Source type: TrialConfidence: Moderate

HRA summary for multiple ascending dose noribogaine PK/PD study

NCT06480981; track trial status, design, endpoints, sponsor, and QT/cardiac monitoring language.

Clinical trials · source_radar

Source
Source type: TrialConfidence: High

Texas will launch its own clinical trials into ibogaine psychedelic after failing to find a drug company to help - KSAT

Research or trial-status source from KSAT. A listing or announcement does not prove safety, efficacy, approval, or availability.

Clinical trials · KSAT

Source
Source type: TrialConfidence: High

TN clears way for clinical trials of ibogaine, same drug classification as LSD - WZTV

Research or trial-status source from WZTV. A listing or announcement does not prove safety, efficacy, approval, or availability.

Clinical trials · WZTV

Source
Source type: TrialConfidence: High

Tennessee lawmakers approve HOPE Act to allow ibogaine clinical trials for addiction - WTVC

Research or trial-status source from WTVC. A listing or announcement does not prove safety, efficacy, approval, or availability.

Clinical trials · WTVC

Source
Source type: TrialConfidence: High

What to know about ibogaine as Texas lawmakers eye clinical trial - USA Today

Research or trial-status source from USA Today. A listing or announcement does not prove safety, efficacy, approval, or availability.

Clinical trials · USA Today

Source