Clinical boundary Schedule I in the U.S. Serious cardiac risk Not FDA-approved No dosing or referrals Schedule I · cardiac risk Not FDA-approved · no referrals

Trials

Clinical trials hub

Every registered human trial of ibogaine or noribogaine this catalog tracks, with phase, current registry status, enrollment, and sponsor. Statuses were pulled directly from ClinicalTrials.gov on 2026-06-11. A registered trial is not evidence of safety or effectiveness — most listed studies are small, early-phase, or observational.

Registered trials

Click any registry ID to read the full official record. Note what is not here: no completed randomized efficacy trial of ibogaine exists. The atai Phase 1/2 study is the largest controlled program to date; its peer-reviewed results determine how much weight it can carry.

Registry ID Title Phase Status Planned/actual N Conditions
NCT04313712Stanford University Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure Observational Active, not recruitingupdated 2024-12-17 30 Blast or Combat Exposure; Head Injury Trauma
NCT07226570University of California, Irvine Mapping Ibogaine Neural Dynamics in Opioid Use Disorder Observational Recruitingupdated 2026-05-15 20 Opioid Use Disorder (OUD)
NCT03380728University of Sao Paulo Ibogaine in the Treatment of Alcoholism: an Open-label Escalating-dose Trial Phase 2 Completedupdated 2024-11-23 9 Alcoholism
NCT04003948International Center for Ethnobotanical Education, Research, and Service Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification Phase 2 Completedupdated 2025-01-16 20 Drug Dependence; Drug Use Disorders; Opioid Dependence
NCT05029401atai Therapeutics, Inc. A Study of Oral Ibogaine in Opioid Withdrawal Phase 1 / Phase 2 Completedupdated 2024-08-05 116 Opiate Withdrawal Syndrome
NCT06480981DemeRx NB Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers Phase 1 Completedupdated 2026-01-05 55 Pharmacokinetics
NCT05516823Psychedelic Data Society Personality and Drug Use Observational Unknown statusupdated 2022-09-27 1000 No Conditions Study Focus on Substance Use and Personality
NCT05180149Quantified Citizen Technologies Inc. Personality and Drug Use (PDU) Observational Withdrawnupdated 2022-04-23 0 Personality
NCT06810765Johns Hopkins University Trifecta Research Study Phase 2 Withdrawnupdated 2025-08-18 0 PTSD - Post Traumatic Stress Disorder; Cognitive Dysfunction; Brain Trauma

Registry statuses change; each row shows its last registry update date. "Completed" means the study finished — it says nothing about results. Educational reference, not medical advice; no dosing, no referrals.